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K Alitalo Selected Research

Vascular Endothelial Growth Factor C

4/2016Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts.
10/2001A model for gene therapy of human hereditary lymphedema.
9/2001Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma.
3/2001Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.
2/2001Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.
2/2001Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.
2/2001Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.
1/2001Involvement of VEGFR-2 (kdr/flk-1) but not VEGFR-1 (flt-1) in VEGF-A and VEGF-C-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro.
10/2000Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta.
8/2000Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.
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K Alitalo Research Topics

Disease

11Neoplasms (Cancer)
11/2001 - 07/2000
5Lymphedema (Milroy Disease)
02/2013 - 08/2000
4Neoplasm Metastasis (Metastasis)
03/2001 - 12/2000
3Breast Neoplasms (Breast Cancer)
03/2001 - 12/2000
2Inflammation (Inflammations)
04/2016 - 02/2013
2Reperfusion Injury
08/2015 - 05/2014
2Fibrosis (Cirrhosis)
02/2013 - 12/2006
1Primary Graft Dysfunction
08/2015
1Weight Gain
08/2014
1Insulin Resistance
08/2014
1Edema (Dropsy)
02/2013
1Colorectal Neoplasms (Colorectal Cancer)
10/2011
1Parkinson Disease (Parkinson's Disease)
09/2011
1Ovarian Neoplasms (Ovarian Cancer)
02/2011
1Melanoma (Melanoma, Malignant)
09/2001
1Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal)
08/2001
1Corneal Neovascularization
07/2001
1Arteriosclerosis
05/2001
1Carcinogenesis
03/2001
1Lymphatic Metastasis
02/2001
1Pathologic Neovascularization
01/2001
1Neointima
10/2000
1Wounds and Injuries (Trauma)
05/2000
1Ulcer
05/2000
1Pre-Eclampsia (Preeclampsia)
03/2000
1Hypoxia (Hypoxemia)
03/2000
1Fetal Growth Retardation (Intrauterine Growth Retardation)
03/2000

Drug/Important Bio-Agent (IBA)

12Vascular Endothelial Growth Factor CIBA
04/2016 - 07/2000
12Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2011 - 03/2000
8Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA
02/2013 - 05/2000
3Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
02/2011 - 03/2000
3Vascular Endothelial Growth Factor DIBA
11/2001 - 02/2001
2Vascular Endothelial Growth Factor BIBA
08/2014 - 07/2001
2Proteins (Proteins, Gene)FDA Link
02/2013 - 05/2000
2AngiopoietinsIBA
02/2011 - 12/2000
2platelet-derived growth factor AIBA
12/2006 - 05/2001
2Platelet-Derived Growth FactorIBA
12/2006 - 05/2001
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2001 - 12/2000
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
06/2001 - 01/2001
1Glucose (Dextrose)FDA LinkGeneric
08/2014
1Angiopoietin-2IBA
05/2014
1CollagenIBA
02/2013
1LipidsIBA
02/2013
1Transcription Factors (Transcription Factor)IBA
10/2011
1Nerve Growth Factors (Neurotrophins)IBA
09/2011
1TIE-2 Receptor (Receptor, TIE 2)IBA
02/2011
1Phosphotransferases (Kinase)IBA
06/2009
1LigandsIBA
12/2006
1Glycoproteins (Glycoprotein)IBA
11/2001
1NeuropilinsIBA
10/2001
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
08/2001
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
07/2001
1Peptides (Polypeptides)IBA
05/2001
1MitogensIBA
05/2001
1Biological ProductsIBA
02/2001
1Collagen Type XVIII (Type XVIII Collagen)IBA
01/2001
1EndostatinsIBA
01/2001
1FibrinIBA
01/2001
1CytokinesIBA
12/2000
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
08/2000
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2000
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
07/2000
1Monoclonal AntibodiesIBA
07/2000
1Laminin (Merosin)IBA
05/2000
1ImmunosorbentsIBA
03/2000
1ErythropoietinFDA Link
03/2000
1EnzymesIBA
03/2000

Therapy/Procedure

4Therapeutics
02/2011 - 07/2000
2Heart Transplantation (Grafting, Heart)
08/2015 - 05/2014
1Drug Therapy (Chemotherapy)
02/2011
1Transplantation
02/2001